R&D Pipeline (In-House)

As of August 2010

Development
Stage
Brand name /
Development Code
Development
Classification
Therapeutic
Target
NDA KMV-0207 Kissei Improvement of postprandial plasma glucose transition in patients with type 2 diabetes mellitus -Mitiglinide / Voglibose combination product -
Phase Ⅲ ※1 KUC-7483 Kissei Overactive bladder
- Beta 3 agonist -
Phase II KPS-0373 In-licensed / Shionogi(Japan) Spinocerebellar ataxia
- Non-peptide mimetic of TRH -
Phase I / II YS110 In-licensed / Y's Therapeutics, University of Tokyo, JST (Japan) Malignant mesothelioma
- Humanized anti-CD26 monoclonal antibody -
Phase I KLH-2109 Kissei Endometriosis/ uterine fibroids
- GnRH antagonist -
Silodosin/
KSO-0400
Kissei Dysuria associated with benign prostatic hyperplasia
- Alfa 1A antagonist -
- Once-daily formulation -
Ozagrel/
KCT-0809
Co-development / Teika(Japan) Dry-eye
- Restoration of corneal and conjunctival epithelium disorder -

※1: KUC-7483: The data of Phase Ⅲ clinical study etc are under detailed analysis.

R&D Pipeline (Out-Licensing)

As of August 2010

Development Stage Generic Name /
Development Code
Development
Company
Territory Therapeutic Target
Approved Silodosin Synmosa
(Taiwan)
Taiwan, Hong Kong Dysuria associated with benign prostatic hyperplasia
NDA Mitiglinide Eisai
(Japan)
※1 ASEAN
(10 countries)
Type 2 diabetes
Silodosin Daiichi Sankyo
(Japan)
China Dysuria associated with benign prostatic hyperplasia
Eisai
(Japan)
※2 ASEAN (10 countries), India, SriLanka
Phase III Mitiglinide Elixir
(U.S.)
North America, Central America, South America Type 2 diabetes
USV
(India)
India
Phase II Bedoradrine MediciNova
(U.S.)
Worldwide, except for Japan Status asthmatics/
Threatened premature labor
Tranilast Nuon Therapeutics
(U.S.)
Worldwide, except for Japan and Korea Rheumatoid arthritis/
Chronic hyperuricemia with gout
Phase I KGA-3235 Dainippon Sumitomo
(Japan)
Japan Type 2 diabetes
GlaxoSmithKline
(U.K.)
Europe, USA, others
Bedoradrine MediciNova
(U.S.)
Worldwide, except for Japan COPD
※1: Approved in Philippines and Thailand, NDA in 2 countries ( NDA in Singapore has been withdrawn ), and NDA preparation in 5 countries
※2: NDA in 2 ASEAN countries
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